19-P033 Functional analyses of axin genes in Schmidtea mediterranea
نویسندگان
چکیده
منابع مشابه
19-P033 Functional analyses of axin genes in Schmidtea mediterranea
the satellite cells. Contaminating CD45+/Mac-1+/Sca-1+ cells were subsequently removed by MACS cell separation. Cell cycle analysis revealed that over 80% of the resulting myogenic cell population was in G0, indicating a high proportion of quiescent cells in the isolated population. RT-PCR analysis showed that the expression of three Kruppel-like factors (Klf) was increased in quiescent satelli...
متن کاملSmedGD: the Schmidtea mediterranea genome database
The planarian Schmidtea mediterranea is rapidly emerging as a model organism for the study of regeneration, tissue homeostasis and stem cell biology. The recent sequencing, assembly and annotation of its genome are expected to further buoy the biomedical importance of this organism. In order to make the extensive data associated with the genome sequence accessible to the biomedical and planaria...
متن کاملSmall RNA pathways in Schmidtea mediterranea.
Planarians are bilaterally symmetrical fresh water organisms capable of regenerating body parts from small fragments following bodily injury. Planarians possess a specialized population of pluripotent cells called neoblasts, which are responsible for their unique regenerative ability. The study of planarian stem cell biology and regeneration has traditionally focused on the transcription factor...
متن کامل19-P022 The roles of Drosophila melanogaster developmental gene orthologues in Schmidtea mediterranea regeneration
The most prominent and dramatic example of regeneration in vertebrates is the complete reconstitution of amphibian limbs and fish fins by epimorphic regeneration. Research into the molecular regulation of this fascinating biological problem is of high medical interest due to the potential application in replacing old or damaged tissues in humans. Retinoic acid (RA), a small lipophilic molecule ...
متن کاملCellular, ultrastructural and molecular analyses of epidermal cell development in the planarian Schmidtea mediterranea.
The epidermis is essential for animal survival, providing both a protective barrier and cellular sensor to external environments. The generally conserved embryonic origin of the epidermis, but the broad morphological and functional diversity of this organ across animals is puzzling. We define the transcriptional regulators underlying epidermal lineage differentiation in the planarian Schmidtea ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2009
ISSN: 0925-4773
DOI: 10.1016/j.mod.2009.06.821